Impaired HCV Clearance in HIV/HCV Coinfected Subjects Treated with PegIFN and RBV Due to Interference of IFN Signaling by IFNαR2a

Enhanced endogenous interferon (IFN) stimulated gene (ISG) signature has been associated with nonresponsiveness to hepatitis C treatment using pegylated-IFNα (pegIFNα) and ribavirin (RBV) in human immunodeficiency virus/hepatitis C virus (HIV/HCV) coinfected patients. Using a proteomic approach, we...

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Detalhes bibliográficos
Main Authors: Lee, Yu-Jin, Zhang, Xiaozhen, Vazquez, Estefania, Shivasabesan, Gayathri, Young, Howard A., Murphy, Alison, Wang, Honghui, Suffredini, Anthony F., Siebenlist, Ulrich, Kottilil, Shyam
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887437/
https://ncbi.nlm.nih.gov/pubmed/24171456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2013.0032
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