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Pre-Existing HCV Variants Resistant to DAAs and Their Sensitivity to PegIFN/RBV in Chinese HCV Genotype 1b Patients

BACKGROUND: The efficacy of direct-acting antiviral agents (DAAs) could be attenuated by the presence of resistance-associated variants (RAVs). The aim of this study was to investigate the natural prevalence of RAVs among Chinese HCV genotype 1b patients and analyze the efficacy of pegylated interfe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Zhang, Yu, Cao, Ying, Zhang, Renwen, Zhang, Xiaxia, Lu, Haiying, Wu, Chihong, Huo, Na, Xu, Xiaoyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094756/
https://ncbi.nlm.nih.gov/pubmed/27812165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165658
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