Impaired HCV Clearance in HIV/HCV Coinfected Subjects Treated with PegIFN and RBV Due to Interference of IFN Signaling by IFNαR2a

Enhanced endogenous interferon (IFN) stimulated gene (ISG) signature has been associated with nonresponsiveness to hepatitis C treatment using pegylated-IFNα (pegIFNα) and ribavirin (RBV) in human immunodeficiency virus/hepatitis C virus (HIV/HCV) coinfected patients. Using a proteomic approach, we...

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Bibliografiske detaljer
Main Authors: Lee, Yu-Jin, Zhang, Xiaozhen, Vazquez, Estefania, Shivasabesan, Gayathri, Young, Howard A., Murphy, Alison, Wang, Honghui, Suffredini, Anthony F., Siebenlist, Ulrich, Kottilil, Shyam
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
Fag:
Research Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887437/
https://ncbi.nlm.nih.gov/pubmed/24171456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2013.0032
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