In Vitro and In Vivo Characterization of a Fully Felinized Therapeutic Anti‐Nerve Growth Factor Monoclonal Antibody for the Treatment of Pain in Cats

BACKGROUND: Limited options are available for the treatment of pain in cats. Monoclonal antibodies (mAbs) that neutralize nerve growth factor (NGF) have demonstrated analgesic capacity in rodent models, people with osteoarthritis, and dogs with degenerative joint disease. HYPOTHESIS/OBJECTIVES: This...

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Detalhes bibliográficos
Publicado no:J Vet Intern Med
Main Authors: Gearing, D.P., Huebner, M., Virtue, E.R., Knight, K., Hansen, P., Lascelles, B.D.X., Gearing, R.P., Drew, A.C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
SMALL ANIMAL
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094543/
https://ncbi.nlm.nih.gov/pubmed/27306920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.13985
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