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A Feline‐Specific Anti‐Nerve Growth Factor Antibody Improves Mobility in Cats with Degenerative Joint Disease–Associated Pain: A Pilot Proof of Concept Study

BACKGROUND: Neutralizing antibodies against nerve growth factor (NGF) are analgesic in rodent models, naturally occurring degenerative joint disease (DJD) pain in dogs, and chronic pain in humans. OBJECTIVES: To evaluate the efficacy of a fully felinized anti‐NGF antibody (NV‐02) for the treatment o...

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Detalhes bibliográficos
Publicado no:J Vet Intern Med
Main Authors: Gruen, M.E., Thomson, A.E., Griffith, E.H., Paradise, H., Gearing, D.P., Lascelles, B.D.X.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153962/
https://ncbi.nlm.nih.gov/pubmed/27334504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.13972
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