In Vitro and In Vivo Characterization of a Fully Felinized Therapeutic Anti‐Nerve Growth Factor Monoclonal Antibody for the Treatment of Pain in Cats

BACKGROUND: Limited options are available for the treatment of pain in cats. Monoclonal antibodies (mAbs) that neutralize nerve growth factor (NGF) have demonstrated analgesic capacity in rodent models, people with osteoarthritis, and dogs with degenerative joint disease. HYPOTHESIS/OBJECTIVES: This...

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Dades bibliogràfiques
Publicat a:J Vet Intern Med
Autors principals: Gearing, D.P., Huebner, M., Virtue, E.R., Knight, K., Hansen, P., Lascelles, B.D.X., Gearing, R.P., Drew, A.C.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
SMALL ANIMAL
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094543/
https://ncbi.nlm.nih.gov/pubmed/27306920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.13985
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