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Phosphoinositide 3-kinase p110δ promotes lumen formation through enhancement of apico-basal polarity and basal membrane organization

Signaling triggered by adhesion to the extracellular matrix plays a key role in the spatial orientation of epithelial polarity and formation of lumens in glandular tissues. Phosphoinositide 3-kinase signaling in particular is known to influence the polarization process during epithelial cell morphog...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Peng, Juan, Awad, Aline, Sar, Sokhavuth, Komaiha, Ola Hamze, Moyano, Romina, Rayal, Amel, Samuel, Didier, Shewan, Annette, Vanhaesebroeck, Bart, Mostov, Keith, Gassama-Diagne, Ama
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094449/
https://ncbi.nlm.nih.gov/pubmed/25583025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6937
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