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PI3K/SHIP2/PTEN pathway in cell polarity and hepatitis C virus pathogenesis

Hepatitis C virus (HCV) infects hepatocytes, polarized cells in the liver. Chronic HCV infection often leads to steatosis, fibrosis, cirrhosis and hepatocellular carcinoma, and it has been identified as the leading cause of liver transplantation worldwide. The HCV replication cycle is dependent on l...

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Bibliographic Details
Published in:World J Hepatol
Main Authors: Awad, Aline, Gassama-Diagne, Ama
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220268/
https://ncbi.nlm.nih.gov/pubmed/28105255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v9.i1.18
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