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Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes

We examined the brains of 266 patients with prion diseases (PrionD) and found that 46 (17%) had Alzheimer disease (AD)-like changes. To explore potential mechanistic links between PrionD and AD, we exposed human brain aggregates (Hu BrnAggs) to brain homogenate from a patient with sporadic Creutzfel...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Tousseyn, Thomas, Bajsarowicz, Krystyna, Sánchez, Henry, Gheyara, Ania, Oehler, Abby, Geschwind, Michael, DeArmond, Bernadette, DeArmond, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094352/
https://ncbi.nlm.nih.gov/pubmed/26226132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000228
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