Selenophosphate Synthetase 1 is an Essential Protein with Roles in Regulation of Redox Homeostasis in Mammals

Selenophosphate synthetase (SPS) was initially detected in bacteria and was shown to synthesize selenophosphate, the active selenium donor. However, mammals have two SPS paralogs, which are designated SPS1 and SPS2. Although it is known that SPS2 catalyzes the synthesis of selenophosphate, the funct...

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Pubblicato in:Biochem J
Autori principali: Tobe, Ryuta, Carlson, Bradley A., Huh, Jang Hoe, Castro, Nadia P., Xu, Xue-Ming, Tsuji, Petra A., Lee, Sang-Goo, Bang, Jeyoung, Na, Ji-Woon, Kong, Young-Yun, Beaglehole, Daniel, Southon, Eileen, Seifried, Harold, Tessarollo, Lino, Salomon, David S., Schweizer, Ulrich, Gladyshev, Vadim N., Hatfield, Dolph L., Lee, Byeong Jae
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094348/
https://ncbi.nlm.nih.gov/pubmed/27208177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160393
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