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Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells

The 15-kDa selenoprotein (Sep15) is a selenoprotein residing in the lumen of the endoplasmic reticulum (ER) and implicated in quality control of protein folding. Herein, we established an inducible RNAi cell line that targets Sep15 mRNA in Chang liver cells. RNAi-induced Sep15 deficiency led to inhi...

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Библиографические подробности
Опубликовано в: :Mol Cells
Главные авторы: Bang, Jeyoung, Huh, Jang Hoe, Na, Ji-Woon, Lu, Qiao, Carlson, Bradley A., Tobe, Ryuta, Tsuji, Petra A., Gladyshev, Vadim N., Hatfield, Dolph L., Lee, Byeong Jae
Формат: Artigo
Язык:Inglês
Опубликовано: Korean Society for Molecular and Cellular Biology 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443288/
https://ncbi.nlm.nih.gov/pubmed/25728752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.0007
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