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Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells

The 15-kDa selenoprotein (Sep15) is a selenoprotein residing in the lumen of the endoplasmic reticulum (ER) and implicated in quality control of protein folding. Herein, we established an inducible RNAi cell line that targets Sep15 mRNA in Chang liver cells. RNAi-induced Sep15 deficiency led to inhi...

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Detalhes bibliográficos
Publicado no:Mol Cells
Main Authors: Bang, Jeyoung, Huh, Jang Hoe, Na, Ji-Woon, Lu, Qiao, Carlson, Bradley A., Tobe, Ryuta, Tsuji, Petra A., Gladyshev, Vadim N., Hatfield, Dolph L., Lee, Byeong Jae
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Molecular and Cellular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443288/
https://ncbi.nlm.nih.gov/pubmed/25728752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.0007
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