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The Hidden Conundrum of Phosphoinositide Signaling in Cancer
Phosphoinositide 3-kinase (PI3K) generation of PI(3,4,5)P(3) from PI(4,5)P(2) and the subsequent activation of Akt and its downstream signaling cascades (e.g. mTORC1) dominates the landscape of phosphoinositide signaling axis in cancer research. However, PI(4,5)P(2) is breaking its boundary as merel...
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| Τόπος έκδοσης: | Trends Cancer |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094282/ https://ncbi.nlm.nih.gov/pubmed/27819060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.05.009 |
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