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Phosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth

The assembly of signaling complexes at the plasma membrane is required for the initiation and propagation of cellular signaling upon cell activation. The class I PI3K and the serine/threonine-specific protein kinase Akt signaling pathways (PI3K/Akt) are often activated in tumors. These pathways are...

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Uloženo v:
Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Thapa, Narendra, Choi, Suyong, Tan, Xiaojun, Wise, Thomas, Anderson, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513138/
https://ncbi.nlm.nih.gov/pubmed/26070568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596742
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