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Phosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth

The assembly of signaling complexes at the plasma membrane is required for the initiation and propagation of cellular signaling upon cell activation. The class I PI3K and the serine/threonine-specific protein kinase Akt signaling pathways (PI3K/Akt) are often activated in tumors. These pathways are...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Thapa, Narendra, Choi, Suyong, Tan, Xiaojun, Wise, Thomas, Anderson, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513138/
https://ncbi.nlm.nih.gov/pubmed/26070568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596742
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