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The Hidden Conundrum of Phosphoinositide Signaling in Cancer
Phosphoinositide 3-kinase (PI3K) generation of PI(3,4,5)P(3) from PI(4,5)P(2) and the subsequent activation of Akt and its downstream signaling cascades (e.g. mTORC1) dominates the landscape of phosphoinositide signaling axis in cancer research. However, PI(4,5)P(2) is breaking its boundary as merel...
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| 出版年: | Trends Cancer |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094282/ https://ncbi.nlm.nih.gov/pubmed/27819060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.05.009 |
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