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The Hidden Conundrum of Phosphoinositide Signaling in Cancer

Phosphoinositide 3-kinase (PI3K) generation of PI(3,4,5)P(3) from PI(4,5)P(2) and the subsequent activation of Akt and its downstream signaling cascades (e.g. mTORC1) dominates the landscape of phosphoinositide signaling axis in cancer research. However, PI(4,5)P(2) is breaking its boundary as merel...

詳細記述

保存先:
書誌詳細
出版年:Trends Cancer
主要な著者: Thapa, Narendra, Tan, Xiaojun, Choi, Suyong, Lambert, Paul F., Rapraeger, Alan C., Anderson, Richard A.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094282/
https://ncbi.nlm.nih.gov/pubmed/27819060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.05.009
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