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Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis
BACKGROUND: The CXCL12/CXCR4 axis transactivates HER2 and promotes intraosseous tumor growth. To further explore the transactivation of HER2 by CXCL12, we investigated the role of small GTP protein G(αi2) in Src and HER2 phosphorylation in lipid raft membrane microdomains and the significance of CXC...
Tallennettuna:
| Julkaisussa: | Mol Cancer |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5093938/ https://ncbi.nlm.nih.gov/pubmed/27809841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0552-0 |
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