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Targeting CXCR4 with CTCE-9908 inhibits prostate tumor metastasis
BACKGROUND: CXCL12/CXCR4 transactivation of epidermal growth factor family receptors in lipid raft membrane microdomains on cell surface is thought to mediate tumor growth and subsequent development of metastatic disease. CTCE-9908 is a known inhibitor of CXCR4. Herein, we tested the efficacy of CTC...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912255/ https://ncbi.nlm.nih.gov/pubmed/24472670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2490-14-12 |
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