mTORC1 inhibitor rapamycin and ER stressor tunicamycin induce differential patterns of ER-mitochondria coupling

Efficient mitochondrial Ca(2+) uptake takes place at contact points between the ER and mitochondria, and represents a key regulator of many cell functions. In a previous study with HeLa cells, we showed that ER-to-mitochondria Ca(2+) transfer increases during the early phase of ER stress induced by...

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Publicat a:Sci Rep
Autors principals: Bravo-Sagua, Roberto, López-Crisosto, Camila, Parra, Valentina, Rodriguez-Peña, Marcelo, Rothermel, Beverly A., Quest, Andrew F.G., Lavandero, Sergio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093439/
https://ncbi.nlm.nih.gov/pubmed/27808250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36394
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