Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways

The invasive and metastatic properties of many human tumors have been associated with upregulation of the microRNA miR-10b, but its functional contributions in this setting have not been fully unraveled. Here we report the generation of miR-10b-deficient mice in which miR-10b is shown to be largely...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kim, Jongchan, Siverly, Ashley N., Chen, Dahu, Wang, Min, Yuan, Yuan, Wang, Yumeng, Lee, Hyemin, Zhang, Jinsong, Muller, William J., Liang, Han, Gan, Boyi, Yang, Xianbin, Sun, Yutong, You, M. James, Ma, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093036/
https://ncbi.nlm.nih.gov/pubmed/27569213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1571
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