miR-100 Induces Epithelial-Mesenchymal Transition but Suppresses Tumorigenesis, Migration and Invasion

Whether epithelial-mesenchymal transition (EMT) is always linked to increased tumorigenicity is controversial. Through microRNA (miRNA) expression profiling of mammary epithelial cells overexpressing Twist, Snail or ZEB1, we identified miR-100 as a novel EMT inducer. Surprisingly, miR-100 inhibits t...

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Detalhes bibliográficos
Main Authors: Chen, Dahu, Sun, Yutong, Yuan, Yuan, Han, Zhenbo, Zhang, Peijing, Zhang, Jinsong, You, M. James, Teruya-Feldstein, Julie, Wang, Min, Gupta, Sumeet, Hung, Mien-Chie, Liang, Han, Ma, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937226/
https://ncbi.nlm.nih.gov/pubmed/24586203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004177
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