Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis.

The frequency and pattern of mutations at codon 61 of the c-Ha-ras gene have been analyzed in 195 liver tumors and 132 precancerous liver lesions from various rodent strains with differing susceptibility to hepatocarcinogenesis. By using the polymerase chain reaction and allele-specific oligonucleot...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Buchmann, A, Bauer-Hofmann, R, Mahr, J, Drinkwater, N R, Luz, A, Schwarz, M
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1991
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1992483/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.3.911
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