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Nonrandom duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors.

We analyzed the normal/mutated allelic ratio of the Ha-ras-1 gene in mouse skin squamous cell carcinomas induced by initiation with dimethylbenz[a]anthracene and promotion with phorbol 12-myristate 13-acetate. DNA for these studies was obtained from short-term tumor cultures (24-72 hr) to eliminate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bianchi, A B, Aldaz, C M, Conti, C J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC54646/
https://ncbi.nlm.nih.gov/pubmed/1697691
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