Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis.

The frequency and pattern of mutations at codon 61 of the c-Ha-ras gene have been analyzed in 195 liver tumors and 132 precancerous liver lesions from various rodent strains with differing susceptibility to hepatocarcinogenesis. By using the polymerase chain reaction and allele-specific oligonucleot...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Buchmann, A, Bauer-Hofmann, R, Mahr, J, Drinkwater, N R, Luz, A, Schwarz, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1992483/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.3.911
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