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Translocation of CD28 to lipid rafts and costimulation of IL-2

Stimulation of the CD28 costimulatory receptor can lead to an increased surface lipid raft expression in T lymphocytes. Here, we demonstrate that CD28 itself is recruited to lipid rafts in both Jurkat and peripheral blood T lymphocytes. This recruitment of CD28 is triggered by engagement with either...

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Autors principals: Sadra, Ali, Cinek, Tomas, Imboden, John B.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC509216/
https://ncbi.nlm.nih.gov/pubmed/15280538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403792101
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