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Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome

The activation of mammalian origins of replication depends so far on ill understood epigenetic events, such as binding of transcription factors, chromatin structure, and nuclear localization. Understanding these mechanisms is not only a scientific challenge but also represents a prerequisite for the...

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Autori principali: Jenke, Andreas C. W., Stehle, Isa M., Herrmann, Frank, Eisenberger, Tobias, Baiker, Armin, Bode, Jürgen, Fackelmayer, Frank O., Lipps, Hans J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC509201/
https://ncbi.nlm.nih.gov/pubmed/15272077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401355101
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