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An episomally replicating vector binds to the nuclear matrix protein SAF-A in vivo

pEPI-1, a vector in which a chromosomal scaffold/matrix-attached region (S/MAR) is linked to the simian virus 40 origin of replication, is propagated episomally in CHO cells in the absence of the virally encoded large T-antigen and is stably maintained in the absence of selection pressure. It has be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jenke, Bok Hee C., Fetzer, Christian P., Stehle, Isa M., Jönsson, Franziska, Fackelmayer, Frank O., Conradt, Harald, Bode, Jürgen, Lipps, Hans J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084058/
https://ncbi.nlm.nih.gov/pubmed/11897664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf070
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