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The ion channel of F-ATP synthase is the target of toxic organotin compounds

ATP is the universal energy currency of living cells, and the majority of it is synthesized by the F(1)F(0) ATP synthase. Inhibitors of this enzyme are therefore potentially detrimental for all life forms. Tributyltin chloride (TBT-Cl) inhibits ATP hydrolysis by the Na(+)-translocating ATP synthase...

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Bibliografiske detaljer
Main Authors: von Ballmoos, Christoph, Brunner, Josef, Dimroth, Peter
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC509188/
https://ncbi.nlm.nih.gov/pubmed/15277681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402869101
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