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An alternative role of F(o)F(1)-ATP synthase in Escherichia coli: synthesis of thiamine triphosphate

In E. coli, thiamine triphosphate (ThTP), a putative signaling molecule, transiently accumulates in response to amino acid starvation. This accumulation requires the presence of an energy substrate yielding pyruvate. Here we show that in intact bacteria ThTP is synthesized from free thiamine diphosp...

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Detalhes bibliográficos
Main Authors: Gigliobianco, Tiziana, Gangolf, Marjorie, Lakaye, Bernard, Pirson, Bastien, von Ballmoos, Christoph, Wins, Pierre, Bettendorff, Lucien
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545222/
https://ncbi.nlm.nih.gov/pubmed/23323214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01071
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