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EGF-Induced VEGF Exerts a PI3K-Dependent Positive Feedback on ERK and AKT through VEGFR2 in Hematological In Vitro Models

EGFR and VEGFR pathways play major roles in solid tumor growth and progression, however, little is known about these pathways in haematological tumors. This study investigated the crosstalk between EGFR and VEGFR2 signaling in two hematological in vitro models: THP1, a human monocytic leukemia, and...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Saryeddine, Lilian, Zibara, Kazem, Kassem, Nouhad, Badran, Bassam, El-Zein, Nabil
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091849/
https://ncbi.nlm.nih.gov/pubmed/27806094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165876
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