Sensitivity of human prostate cancer cells to chemotherapeutic drugs depends on EndoG expression regulated by promoter methylation

Analysis of promoter sequences of all known human cytotoxic endonucleases showed that endonuclease G (EndoG) is the only endonuclease that contains a CpG island, a segment of DNA with high G+C content and a site for methylation, in the promoter region. A comparison of three human prostate cancer cel...

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Publicado en:Cancer Lett
Autores principales: Wang, Xiaoying, Tryndyak, Volodymyr, Apostolov, Eugene O., Yin, Xiaoyan, Shah, Sudhir V., Pogribny, Igor P., Basnakian, Alexei G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091799/
https://ncbi.nlm.nih.gov/pubmed/18565644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.04.053
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