Leishmania infantum EndoG Is an Endo/Exo-Nuclease Essential for Parasite Survival

EndoG, a member of the DNA/RNA non-specific ββα-metal family of nucleases, has been demonstrated to be present in many organisms, including Trypanosomatids. This nuclease participates in the apoptotic program in these parasites by migrating from the mitochondrion to the nucleus, where it takes part...

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Detalles Bibliográficos
Main Authors: Rico, Eva, Oliva, Cristina, Gutierrez, Kilian Jesús, Alzate, Juan Fernando, Genes, Carlos Mario, Moreno, David, Casanova, Elena, Gigante, Alba, Pérez-Pérez, María-Jesús, Camarasa, María-José, Clos, Joachim, Gago, Federico, Jiménez-Ruiz, Antonio
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971528/
https://ncbi.nlm.nih.gov/pubmed/24651293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089526
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