Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.

Thromboxane A2 (TXA2) is a labile metabolite of arachidonic acid that has potent biological effects. Its actions are mediated by G protein-coupled thromboxane-prostanoid (TP) receptors. TP receptors have been implicated in the pathogenesis of cardiovascular diseases. To investigate the physiological...

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Udgivet i:J Clin Invest
Main Authors: Thomas, D W, Mannon, R B, Mannon, P J, Latour, A, Oliver, J A, Hoffman, M, Smithies, O, Koller, B H, Coffman, T M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509152/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5116
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