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Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene

Adrenomedullin (AM) is a multifunctional peptide vasodilator that is essential for life. To date, numerous in vitro studies have suggested that AM can mediate its biological effects through at least three different receptors. To determine the in vivo importance of the most likely candidate receptor,...

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Detalhes bibliográficos
Main Authors: Dackor, Ryan T., Fritz-Six, Kimberly, Dunworth, William P., Gibbons, Carrie L., Smithies, Oliver, Caron, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430335/
https://ncbi.nlm.nih.gov/pubmed/16537897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.7.2511-2518.2006
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