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The effects of a repeated dose of a recombinant humanized anti-cocaine monoclonal antibody on cocaine self-administration in rats

BACKGROUND: Immunotherapy has shown potential as a treatment for cocaine abuse. The humanized recombinant anti-cocaine monoclonal antibody (mAb) with the preclinical designation h2E2 has been shown to decrease cocaine concentrations in the brain in rats, but its effects on cocaine self-administratio...

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Publicat a:Drug Alcohol Depend
Autors principals: Wetzel, Hanna N., Tsibulsky, Vladimir L., Norman, Andrew B.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091287/
https://ncbi.nlm.nih.gov/pubmed/27736682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2016.09.024
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