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The effects of a repeated dose of a recombinant humanized anti-cocaine monoclonal antibody on cocaine self-administration in rats
BACKGROUND: Immunotherapy has shown potential as a treatment for cocaine abuse. The humanized recombinant anti-cocaine monoclonal antibody (mAb) with the preclinical designation h2E2 has been shown to decrease cocaine concentrations in the brain in rats, but its effects on cocaine self-administratio...
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| Veröffentlicht in: | Drug Alcohol Depend |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5091287/ https://ncbi.nlm.nih.gov/pubmed/27736682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2016.09.024 |
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