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A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats

A recombinant humanized anticocaine monoclonal antibody, h2E2, has shown potential in the preclinical phases for the treatment of cocaine abuse. The standard tests for cocaine usage are the detection of benzoylecgonine (BE) and cocaine in the urine. This includes workplace drug screens as well as in...

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Bibliografiske detaljer
Udgivet i:Drug Metab Dispos
Main Authors: Marckel, Jordan A., Wetzel, Hanna N., Amlal, Sihame, Amlal, Hassane, Norman, Andrew B.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367686/
https://ncbi.nlm.nih.gov/pubmed/30578276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.118.083857
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