Targeting HMGA2 in Retinoblastoma Cells in vitro Using the Aptamer Strategy

High-mobility group A2 (HMGA2) protein regulates retinoblastoma (RB) cancer cell proliferation. Here, a stable phosphorothioate-modified HMGA2 aptamer was used to block HMGA2 protein function in RB cells. HMGA2-aptamer internalisation in RB cells (Y79, Weri Rb1) and non-neoplastic human retinal cell...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ocul Oncol Pathol
Päätekijät: Nalini, Venkatesan, Deepa, Perinkulam Ravi, Raguraman, Rajeswari, Khetan, Vikas, Reddy, Maddy Ashwin, Krishnakumar, Subramanian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: S. Karger AG 2016
Aiheet:
Basic Science Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091129/
https://ncbi.nlm.nih.gov/pubmed/27843907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447300
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia