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Targeting HMGA2 in Retinoblastoma Cells in vitro Using the Aptamer Strategy
High-mobility group A2 (HMGA2) protein regulates retinoblastoma (RB) cancer cell proliferation. Here, a stable phosphorothioate-modified HMGA2 aptamer was used to block HMGA2 protein function in RB cells. HMGA2-aptamer internalisation in RB cells (Y79, Weri Rb1) and non-neoplastic human retinal cell...
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| Publicat a: | Ocul Oncol Pathol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
S. Karger AG
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5091129/ https://ncbi.nlm.nih.gov/pubmed/27843907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447300 |
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