Acid Sphingomyelinase Mediates Oxidized-LDL Induced Apoptosis in Macrophage via Endoplasmic Reticulum Stress

Aim: Macrophage apoptosis is a vital event in advanced atherosclerosis, and oxidized low-density lipoprotein (ox-LDL) is a major contributor to this process. Acid sphingomyelinase (ASM) and ceramide are also involved in the induction of apoptosis, particularly in macrophages. Our current study focus...

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Detalhes bibliográficos
Publicado no:J Atheroscler Thromb
Main Authors: Zhao, Min, Pan, Wei, Shi, Rui-zheng, Bai, Yong-ping, You, Bo-yang, Zhang, Kai, Fu, Qiong-mei, Schuchman, Edward H., He, Xing-xuan, Zhang, Guo-gang
Formato: Artigo
Idioma:Inglês
Publicado em: Japan Atherosclerosis Society 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090817/
https://ncbi.nlm.nih.gov/pubmed/26923251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.32383
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