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Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity
The interferon‐induced transmembrane (IFITM) proteins protect host cells from diverse virus infections. IFITM proteins also incorporate into HIV‐1 virions and inhibit virus fusion and cell‐to‐cell spread, with IFITM3 showing the greatest potency. Here, we report that amino‐terminal mutants of IFITM3...
Guardat en:
| Publicat a: | EMBO Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5090704/ https://ncbi.nlm.nih.gov/pubmed/27601221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642771 |
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