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Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity
The interferon‐induced transmembrane (IFITM) proteins protect host cells from diverse virus infections. IFITM proteins also incorporate into HIV‐1 virions and inhibit virus fusion and cell‐to‐cell spread, with IFITM3 showing the greatest potency. Here, we report that amino‐terminal mutants of IFITM3...
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| 出版年: | EMBO Rep |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5090704/ https://ncbi.nlm.nih.gov/pubmed/27601221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642771 |
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