Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo.

Perlecan, a ubiquitous heparan sulfate proteoglycan, possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). In this report we blocked perlecan expression by using either constitutive CMV-driven or doxycycline- inducible an...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Sharma, B, Handler, M, Eichstetter, I, Whitelock, J M, Nugent, M A, Iozzo, R V
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC509011/
https://ncbi.nlm.nih.gov/pubmed/9788974
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items