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Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo.

Perlecan, a ubiquitous heparan sulfate proteoglycan, possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). In this report we blocked perlecan expression by using either constitutive CMV-driven or doxycycline- inducible an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sharma, B, Handler, M, Eichstetter, I, Whitelock, J M, Nugent, M A, Iozzo, R V
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC509011/
https://ncbi.nlm.nih.gov/pubmed/9788974
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