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A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor.

Perlecan, a widespread heparan sulphate (HS) proteoglycan, is directly involved in the storing of angiogenic growth factors, mostly members of the fibroblast growth factor (FGF) gene family. We have previously shown that antisense targeting of the perlecan gene causes a reduced growth and responsive...

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Autores principales: Ghiselli, G, Eichstetter, I, Iozzo, R V
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222131/
https://ncbi.nlm.nih.gov/pubmed/11563979
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