Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy.

Numerous studies have implicated Coxsackievirus in acute and chronic heart failure. Although enteroviral nucleic acids have been detected in selected patients with dilated cardiomyopathy, the significance of such persistent nucleic acids is unknown. To investigate the mechanisms by which restricted...

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Detalhes bibliográficos
Main Authors: Wessely, R, Klingel, K, Santana, L F, Dalton, N, Hongo, M, Jonathan Lederer, W, Kandolf, R, Knowlton, K U
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508992/
https://ncbi.nlm.nih.gov/pubmed/9769337
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