A Role for Toll-like Receptor 3 Variants in Host Susceptibility to Enteroviral Myocarditis and Dilated Cardiomyopathy

The innate antiviral response is mediated, at least in part, by Toll-like receptors (TLRs). TLR3 signaling is activated in response to viral infection, and the absence of TLR3 in mice significantly increases mortality after infection with enteroviruses that cause myocarditis and/or dilated cardiomyo...

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Hlavní autoři: Gorbea, Carlos, Makar, Kimberly A., Pauschinger, Matthias, Pratt, Gregory, Bersola, Jeathrina L. F., Varela, Jacquelin, David, Ryan M., Banks, Lori, Huang, Chien-Hua, Li, Hua, Schultheiss, Heinz-Peter, Towbin, Jeffrey A., Vallejo, Jesús G., Bowles, Neil E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906314/
https://ncbi.nlm.nih.gov/pubmed/20472559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047464
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