Use of Cation Exchange Chromatography for Human C-peptide Isotope Dilution – Mass Spectrometric Assay

An application of ion exchange chromatography for C-peptide analysis is described here. At the stage of C-peptide isolation, a strong cation exchanger (SP HP or MonoS) was used to purify the analyte from ballast proteins and peptides. The conditions of ion-exchange chromatographic separations were o...

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Bibliographic Details
Published in:J Chromatogr A
Main Authors: Stoyanov, Alexander V., Rohlfing, Curt L., Connolly, Shawn, Roberts, Matthew L., Nauser, Christopher L., Little, Randie R.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089808/
https://ncbi.nlm.nih.gov/pubmed/22098929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2011.10.080
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