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Two-step Ion-exchange chromatographic purification combined with reversed-phase chromatography to isolate C-peptide for mass spectrometric analysis

A liquid chromatography with mass spectrometry on-line platform that includes the orthogonal techniques of ion exchange and reversed phase chromatography is applied for C-peptide analysis. Additional improvement is achieved by the subsequent application of cation- and anion-exchange purification ste...

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Detalles Bibliográficos
Publicado en:J Sep Sci
Main Authors: Kabytaev, Kuanysh, Durairaj, Anita, Shin, Dmitriy, Rohlfing, Curt L., Connolly, Shawn, Little, Randie R., Stoyanov, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053671/
https://ncbi.nlm.nih.gov/pubmed/26717885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jssc.201500989
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