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Characterization of heme oxygenase and biliverdin reductase gene expression in zebrafish (Danio rerio): Basal expression and response to pro-oxidant exposures

While heme is an important cofactor for numerous proteins, it is highly toxic in its unbound form and can perpetuate the formation of reactive oxygen species. Heme oxygenase enzymes (HMOX1 and HMOX2) degrade heme into biliverdin and carbon monoxide, with biliverdin subsequently being converted to bi...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Holowiecki, Andrew, O’Shields, Britton, Jenny, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089712/
https://ncbi.nlm.nih.gov/pubmed/27671773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.09.022
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