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Identification and quantification of histone PTMs using high-resolution mass spectrometry

DNA is organized into nucleosomes, composed of 147 base pairs of DNA wrapped around an octamer of histone proteins including H2A, H2B, H3, and H4. Histones are critical regulators of many nuclear processes, including transcription, DNA damage repair, and higher order chromatin structure. Much of the...

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Detalles Bibliográficos
Publicado en:Methods Enzymol
Main Authors: Karch, Kelly R., Sidoli, Simone, Garcia, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089704/
https://ncbi.nlm.nih.gov/pubmed/27423855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.12.007
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