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Identification and quantification of histone PTMs using high-resolution mass spectrometry

DNA is organized into nucleosomes, composed of 147 base pairs of DNA wrapped around an octamer of histone proteins including H2A, H2B, H3, and H4. Histones are critical regulators of many nuclear processes, including transcription, DNA damage repair, and higher order chromatin structure. Much of the...

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Détails bibliographiques
Publié dans:Methods Enzymol
Auteurs principaux: Karch, Kelly R., Sidoli, Simone, Garcia, Benjamin A.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089704/
https://ncbi.nlm.nih.gov/pubmed/27423855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.12.007
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